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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS12 All Species: 21.52
Human Site: S402 Identified Species: 39.44
UniProt: Q96CB8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CB8 NP_001135943.1 462 48808 S402 P G S S S Q L S G N G N S G T
Chimpanzee Pan troglodytes XP_517380 462 48786 S402 P G S S S Q L S G N G N S G T
Rhesus Macaque Macaca mulatta XP_001084188 462 48791 S402 P G N S S Q L S G N G N T G T
Dog Lupus familis XP_545012 788 84125 S728 P G N T S Q L S G N G N S G T
Cat Felis silvestris
Mouse Mus musculus Q9D168 461 48550 S401 P G G S S Q L S G N G N S A T
Rat Rattus norvegicus Q68FR3 461 48459 S401 P G G S S Q L S G N G N S A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511131 200 19036 A155 A G A S G S A A G K A A S D P
Chicken Gallus gallus XP_420500 509 53231 Q447 T V P S T S S Q V S S G N G N
Frog Xenopus laevis Q6DJM6 464 48894 L399 S S G S V S S L S S Q L G S N
Zebra Danio Brachydanio rerio Q6IQU7 479 49572 G404 V T G S L S P G A A P S S S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651507 328 34315 A283 T A A S S L S A I G G M E K H
Honey Bee Apis mellifera XP_393298 287 32118 D242 N I H I I S A D R R L K D M M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195035 333 36996 N288 F I G P G E G N V E Q L G I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.9 54.9 N.A. 91.3 90.6 N.A. 29 73.2 67.4 60.1 N.A. 22.5 23.5 N.A. 25.1
Protein Similarity: 100 99.7 99.7 56.3 N.A. 95.8 95.4 N.A. 32.6 79.1 76.7 72.4 N.A. 39.3 37.4 N.A. 38.7
P-Site Identity: 100 100 86.6 86.6 N.A. 86.6 86.6 N.A. 26.6 13.3 6.6 13.3 N.A. 20 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 40 33.3 13.3 20 N.A. 33.3 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 0 0 0 16 16 8 8 8 8 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 8 0 0 8 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 54 39 0 16 0 8 8 54 8 54 8 16 39 8 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 16 0 8 8 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % K
% Leu: 0 0 0 0 8 8 47 8 0 0 8 16 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 8 % M
% Asn: 8 0 16 0 0 0 0 8 0 47 0 47 8 0 16 % N
% Pro: 47 0 8 8 0 0 8 0 0 0 8 0 0 0 8 % P
% Gln: 0 0 0 0 0 47 0 8 0 0 16 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % R
% Ser: 8 8 16 77 54 39 24 47 8 16 8 8 54 16 0 % S
% Thr: 16 8 0 8 8 0 0 0 0 0 0 0 8 0 47 % T
% Val: 8 8 0 0 8 0 0 0 16 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _